Anti-HLA E antibody [MEM-E/02] ab2216 from Abcam

Product Specs
ItemAnti-HLA E antibody [MEM-E/02]
CompanyAbcam
Price Pricing Info Supplier Page View Supplier Product Page
Catalog Numberab2216
Antibody TypePrimary
HostMouse, Nude mouse
ApplicationsFlow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
CloneMEM-E/02
Quantity100 UG
ClonalityMonoclonal
IsotypeIgG1
Conjugate/TagUnconjugated
FormatPurified from ascities by protein-A affinity chromatography
Concentration1 mg/ml
Gene NameHLA-E
ValidationKnockOut Validated
ReactivityHuman
TargetHLA E

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) HLA-E and Its Soluble Form as Indicators of a Sex-Specific Immune Response in Patients with Oral Squamous Cell CarcinomaInternational Journal of Molecular SciencesNovember 24, 2023Anne Radermacher, Michael Fehrenz, Tamara Bellin, Carolina Claßen, Laura Möller, Ann-Kristin Struckmeier, Mathias Wagner, Philipp Wartenberg, Julius Moratin, Christian Freudlsperger, et al.(Vector Laboratories) (30 min, humid chamber). The first anti-HLA-E antibody (Anti-HLA E antibody [MEM-E/02] (ab2216)) (1:150) (Abcam, Cambridge, UK) was added to the slides and incubated overnight (4° C, humid chamber).

(2) NKG2A and circulating extracellular vesicles are key regulators of natural killer cell activity in prostate cancer after prostatectomyMolecular OncologyMarch 27, 2023Yu‐Chuan Lu, Chen‐Hsun Ho, Jian‐Hua Hong, Ming‐Chieh Kuo, Yi‐An Liao, Fu‐Shan Jaw, Jason Chia‐Hsien Cheng, Chao‐Yuan Huang, Ko‐Ping Chang, Chung‐Hsin Chen, et al.human leukocyte antigen E (HLAE) were targeted with primary antibodies (1 : 1000; AB62540, AB176566, AB2216, and AB124783, respectively; Abcam, Cambridge, MA, USA) and corresponding secondary antibodies. CD63,

(3) Histological Characterization of Class I HLA Molecules in Whole Umbilical Cord Tissue Towards an Inexhaustible Graft Alternative for Reconstructive SurgeryBioengineering (Basel, Switzerland)January 12, 2023Yao YY, Lee DK, Jarvi S, Farshadi M, Sheng M, Mar S, Nevo O, Leong HS.Exbio, Vestec, Czechia), and a mouse monoclonal anti-human HLA-E at 5.0 µg/mL (Clone MEM-E/02; Cat ab2216, Abcam, Cambridge, UK). The negative isotype controls were used at the same working concentration as

(4) Proteomic Alterations and Novel Markers of Neurotoxic Reactive Astrocytes in Human Induced Pluripotent Stem Cell ModelsFrontiers in Molecular NeuroscienceMay 3, 2022David Labib et al.post-mortem samples,1:50,R&D Systems,MAB1561 HLA-E,hiPSC-astrocytes and post-mortem samples,1:50,Abcam,Ab2216 BST2,hiPSC-astrocytes and post-mortem samples,1:100,Abcam,Ab88523 VCAM1,hiPSC-astrocytes and post-mortem

(5) Lesion human leukocyte antigen-E is associated with favourable prognosis for patients with oesophageal squamous cell carcinomaJournal of International Medical ResearchOctober 7, 2021Yong-Fu Xu, Xue-Feng Du, Zhen-Yu Li, Zhe-Ping Fang, Fa-Biao ZhangHLA-E in tumour cells were determined using the mouse monoclonal antibody MEM-E/02 (1:100 dilution, ab2216; Abcam®, Cambridge, MA, USA) that binds to the heavy-chain polypeptides of human HLA-E. Immunohistochemistry

(6) NK Cells Lose Their Cytotoxicity Function against Cancer Stem Cell-Rich Radiotherapy-Resistant Breast Cancer Cell PopulationsInternational journal of molecular sciencesSeptember 6, 2021Jin H, Kim HJ.Abcam), anti-HIF-1α (#ab2185, 1:1000, Abcam), anti-MICA/B (#ab203679, 1:1000, Abcam), anti-HLA-E (#ab2216, 1:1000, Abcam), anti-ADAM-10 (#ab1997, 1:1000, Abcam), and anti-β-actin (#MA5-15739, Thermo Fisher

(7) Effects of HER Family–targeting Tyrosine Kinase Inhibitors on Antibody-dependent Cell-mediated Cytotoxicity in HER2-expressing Breast CancerClinical Cancer ResearchFebruary 1, 2021Denis M. Collins et al.pEGFR Y992 (CST #2235) and pEGFR Y1068 (Millipore #07–818), MHC Class I (Abcam #ab52922) HLA-E (Abcam #ab2216), PD-L1 Clone E1L3N (CST #13684), Alpha-tubulin (Sigma #T6199) primary antibodies. Mouse (Sigma #A6782)

(8) Prognostic value of HLA class I, HLA-E, HLA-G and Tregs in rectal cancer: a retrospective cohort studyBMC CancerDecember 1, 2014Marlies S Reimers, Charla C Engels, Hein Putter, Hans Morreau, Gerrit Jan Liefers, Cornelis J H van de Velde, Peter J K Kuppenidentification [35,36]. For HLA-E and HLA-G identification mouse monoclonal antibodies against HLA-E (ab2216 clone MEM-E/02: AbCam) and HLA-G (4H84: Exbio, Czech Republic) were used [32]. MEM-E/02 recognizes denatured

(9) Inhibition of ERK and proliferation in NK cell lines by soluble HLA-E released from Japanese encephalitis virus infected cellsImmunology lettersNovember 1, 2014Shwetank, Onkar Sanjay Date, Ennio Carbone, Ramanathapuram Manjunath

(10) Immunological subtypes in breast cancer are prognostic for invasive ductal but not for invasive lobular breast carcinomaBritish Journal of CancerJuly 29, 2014C C Engels, D B Y Fontein, P J K Kuppen, E M de Kruijf, V T H B M Smit, J W R Nortier, G J Liefers, C J H van de Velde, E Bastiaannetrespectively) and non-classical HLA class I molecules using mouse monoclonal antibodies against HLA-E (ab2216, clone MEM-E/02: Abcam) and HLA-G; ultimately, Treg infiltration was determined using anti-FoxP3 antibody

(11) Combined analysis of HLA class I, HLA-E and HLA-G predicts prognosis in colon cancer patientsBritish Journal of CancerJanuary 21, 2014E C M Zeestraten, M S Reimers, S Saadatmand, Inès J Goossens-Beumer, J-W T Dekker, G J Liefers, P J van den Elsen, C J H van de Velde, P J K KuppenGenerali et al, 2009). For HLA-E and HLA-G identification, mouse monoclonal antibodies against HLA-E (ab2216 clone MEM-E/02: AbCam, UK) and HLA-G (4H84: Exbio, Czech Republic) were used. MEM-E/02 recognises denatured

(12) Infection of Human Endothelial Cells by Japanese Encephalitis Virus: Increased Expression and Release of Soluble HLA-EPLoS ONENovember 13, 2013Shwetank, Onkar S. Date, Kwang S. Kim, Ramanathapuram Manjunath

(13) Cytotoxic NKG2C+ CD4 T cells target oligodendrocytes in multiple sclerosisJournal of immunology (Baltimore, Md. : 1950)March 15, 2013Zaguia F, Saikali P, Ludwin S, Newcombe J, Beauseigle D, McCrea E, Duquette P, Prat A, Antel JP, Arbour N.

(14) Herpes B Virus, Macacine Herpesvirus 1 , Breaks Simplex Virus Tradition via Major Histocompatibility Complex Class I Expression in Cells from Human and Macaque HostsJournal of VirologyDecember 1, 2012Mugdha Vasireddi, Julia Hilliard

(15) HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8 ⁺ T lymphocytesProceedings of the National Academy of SciencesJune 28, 2011Marloes Gooden, Margit Lampen, Ekaterina S. Jordanova, Ninke Leffers, J. Baptist Trimbos, Sjoerd H. van der Burg, Hans Nijman, Thorbald van HallTMA sections were stained with mouse monoclonal antibodies recognizing HLA-E (clone MEM-E/02; Abcam; ab2216). To detect NK cells, parafﬁn sections were stained with anti-CD56 (clone 1B6, Monosan) and anti-NKp46

(16) HLA-E and HLA-G expression in classical HLA class I-negative tumors is of prognostic value for clinical outcome of early breast cancer patientsJournal of immunology (Baltimore, Md. : 1950)December 15, 2010Esther M de Kruijf, Anita Sajet, Johanna G H van Nes, Russ Natanov, Hein Putter, Vincent T H B M Smit, Gerrit Jan Liefers, Peter J van den Elsen, Cornelis J H van de Velde, Peter J K Kuppen

(17) The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradationJournal of Experimental MedicineAugust 30, 2010Boyoun Park, Eric Spooner, Brandy L. Houser, Jack L. Strominger, Hidde L. Ploegh

(18) The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organellePLoS pathogensApril 1, 2009Grotzke JE, Harriff MJ, Siler AC, Nolt D, Delepine J, Lewinsohn DA, Lewinsohn DM.

(19) Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I moleculesHuman immunologyMarch 1, 2003Catherine Menier, Berta Saez, Vaclav Horejsi, Silvia Martinozzi, Irene Krawice-Radanne, Sylvie Bruel, Caroline Le Danff, Murielle Reboul, Ivan Hilgert, Michèle Rabreau, Mur Luis Larrad, Marika Pla, Edgardo D Carosella, Nathalie Rouas-Freiss

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Anti-HLA E antibody [MEM-E/02] from Abcam

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Anti-HLA E antibody [MEM-E/02] from Abcam

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